Features of Clinical Use of Brexpiprazole, the New Atypical Antipsychotic of the Third Generation: Experience and Perspectives

Background : personalized approach considering the effectiveness and safety of medication is main goal contemporary psychopharmacotherapy. Knowing special characteristics any given drug allows a practitioner to choose tactic meeting needs particular patient. The aim this narrative review was summarize data about use Brexpiprazole in pharmacotherapy different mental disorders. Method using keywords “brexpiprazole”, “psychoses”, “treatment” we performed scientific publications search PubMed PsychInfo databases over last 10 years. Results brexpiprazole supposed resemble such third generation antypsychotics as aripiprazole cariprazine, lacking their drawbacks. There history schizophrenia unipolar depression. Pilot studies clinical cases were presented on possible perspectives brexpiprazole, Alzheimer disease, posttraumatic stress disorder, borderline personality disorder bipolar affective disorder. On basis reviewed conclude that effective for cupping maintenance treatment schizophrenia, augmentation recurrent depressive also perspective other fields psychiatry. has favorable profile with low incidence metabolic, extrapyramidal hyperstimulation symptoms.